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Hou et al (2005) researched the autonomic effects of modafinil in human beings. They discovered that modafinil influences the locus coeruleus, which mediates pupil diameter and arousal, but it doesn't impact other autonomic features, which can be controlled by noreadrenergic Regulate centers (A1 – A5) Positioned outside of the locus coeruleus.Spe
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